Study Shows How Inadequate Sleep Can Jeopardize Brain Organization in Early Adolescence

*The following is excerpted from an online article posted by News Medical.

We know that many teens and preteens get too little or poor-quality sleep. Now, a large, first-of-its kind study from Boston Children’s Hospital spells out in detail how inadequate sleep can jeopardize brain organization in early adolescence.

Researchers from Boston Children’s Sleep Center, analyzed sleep and brain imaging data from more than 5,500 early adolescents (ages 9 to 11 years). The data are from the long-running, NIH-funded Adolescent Brain Cognitive Development (ABCD) study.

The sleep data were reported by parents on a 26-item survey with questions on sleep duration, sleep latency (time it typically takes the child to fall asleep), waking from sleep, difficulty falling back to sleep, difficulty breathing, snoring, nightmares, difficulty waking up, daytime sleepiness, and more.

The brain data came from functional magnetic resonance imaging (fMRI) performed at rest, independent of any task.

A rigorous computational analysis revealed that shorter sleep duration, longer sleep latency, frequent waking, and sleep-disordered breathing were associated with less efficient, flexible, and resilient brain networks. The researchers also observed abnormal network changes in specific parts of the brain: multiple cortical areas as well as the thalamus, basal ganglia, hippocampus, and cerebellum. The detrimental effects were widespread, from individual regions of the brain to large-scale circuits and the entire brain, and many appeared to be independent of unhealthy weight, which also negatively affected sleep quantity and quality.

“The network abnormalities we identified can potentially lead to deficits in multiple cognitive processes, including attention, reward, emotional regulation, memory, and the ability to plan, coordinate, and control actions and behaviors,” says Caterina Stamoulis, PhD, and Lead Researcher.

The study provided additional findings on sleep:

• Girls slept less than boys, averaging 8 to 9 hours of sleep as compared with 9-11 hours for boys. They also took longer to fall asleep.
• Non-white children slept less than white children, averaging 8 to 9 hours versus 9 to 11 hours.
• Higher family income was significantly associated with longer sleep duration.
• Longer screen time were significantly associated with shorter sleep duration.
• Being overweight was associated with shorter sleep duration, more movement during the night, sweating, snoring, difficulty waking, and daytime sleepiness.

The findings appeared in the journal Cerebral Cortex Communications.

Source: News Medical
https://www.news-medical.net/news/20211122/Study-shows-how-inadequate-sleep-can-jeopardize-brain-organization-in-early-adolescence.aspx